Dr. Masako Shimamura’s lab studies dysregulated immune responses to viral infections in immunocompromised hosts, including infants with congenital cytomegalovirus (cCMV) infection. The postdoc will lead analysis of PBMC CITE-seq datasets to understand disease severity and outcomes in cCMV infected infants and design in-vitro studies to elucidate impaired T cell responses. Secondary analyses will explore cytotoxic NK cells and antigen-presenting cells roles. Experience in viral immunology, APC biology, and bioinformatics is desirable. Responsibilities include designing experiments, developing protocols, conducting research under faculty guidance, training technical staff, recording and analyzing data, preparing scientific papers, presenting findings, collaborating with research efforts at NCH and The Ohio State University, and working toward research independence and funding acquisition. Requires PhD or equivalent, research experience from PhD program, excellent interpersonal, laboratory, and computer skills, and ability to manage projects. Physical requirements include occasional bending, climbing, lifting (11-20 lbs), frequent lifting (0-10 lbs), standing, walking, and continuous use of various sensory and motor skills. Workload pressure varies with deadlines for research and manuscript writing.
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